This is the first title in the ULLA Series: a new and innovative line of introductory textbooks on pharmaceutical science for postgraduate students produced by the ULLA Consortium (European Consortium for Advanced Pharmaceutical Education and Research)

Toxicology studies are carried out on all drug substances to ensure safety. This book provides an overview of the methodology andrequirements of pre-clinical safety assessments of new medicines. With the focus on medicinal drugs - the most important safety issues of drugs are covered, including registration requirements of new drugs and pharmacovigilance.

After a general introduction and a number of chapters on basic toxicological principles, organ toxicity of drugs is illustrated by chapters on toxicity in the liver, in the kidney, in the respiratory system and in the immune system.

This is an introductory text for students at BSc, MSc and PhD levels,and will be an excellent companion to pharmacology textbooks, combining a broad treatment of the issues relevant for assessing the safety/efficacy balance of a new drug with information on the toxicological knowledge base and methodology.