Cardiology
- Containing more than 10 pages of color photographs, this guide
- reviews the results of key clinical studies that demonstrate the role that progessive cardiac remodeling plays in the progression of heart failure
- presents new and emerging therapies for the treatment of remodeling, including the use of stem cell and gene transfer therapies
- provides broad coverage of the complex relationships between cardiac injury, the remodeling process, and the development of cardiac dysfunction
- focuses on molecular and cellular mechanisms of action including alterations in gene expression, the role of apoptosis and myocyte regeneration, oxidative stress, and neurohormonal activation in cardiac remodeling
- extensively analyzes clinical trials results that relate changes in remodeling to beneficial clinical outcomes such as a reduction in the progression of heart failure and improved survival rates
Exploring the causes, mechanisms, and pathophysiology of cardiac remodeling, this reference offers detailed descriptions of the various components of the remodeling process, as well as new therapeutic interventions and recent and future prospects for the treatment of cardiac remodeling.