• Serving as the most in-depth and up-to-date source on the subject, this guide
• offers a wide breadth of coverage of the scientific and clinical aspects of cough
• reviews animal studies on the mechanisms of ACE inhibitor-induced cough
• examines the epidemiology, pathophysiology, and pathology of cough-variant asthma
• discusses the Leicester Cough Questionnaire and its use in clinical and research settings
• provides clinical advice on cough challenge methodology for those wishing to establish this facility in their departments

A comprehensive review of the scientific and clinical aspects of acute and chronic cough, this reference focuses on recent developments in our understanding of the molecular biology of putative cough receptors, the neural mechanisms involved in the afferent and efferent limbs, the central processing of the cough reflex, and peptides and other substances that may mediate or modulate the cough reflex. With chapters written by acknowledged authorities in the field, this handbook covers current and potential therapeutic agents, various methodologies to measure cough reflex sensitivity, and clinical approaches for the assessment of chronic cough in adults and children.