• Reviewing current information on the pathophysiology of acid-base disorders from both a molecular and integrative perspective, this book
• provides straightforward guidelines for the diagnosis and management of disturbances of acid-base homeostasis
• includes a discussion of the Stewart approach for the analysis of acid-base chemistry in terms of the independent and dependent variables
• reviews recent advances in the molecular biology of renal acid-base transporters, as well as animal and human studies of acid-base balance
• offers a comprehensive view of metabolic acidosis with separate chapters on all the major forms
• studies the roles of chloride, potassium, and extracellular fluid volume in the pathophysiology of metabolic alkalosis
• covers the unique nature of acid-base balance and acid-base disorders in patients with end-stage renal disease receiving renal replacement therapy
• covers acid-base disorders in children
• demonstrates the use of effective diagnostic tools using case studies gleaned from the authors' personal experiences

With detailed contributions and research from experts in the physiology of normal acid-base homeostasis and the management of acid-base disorders, this reference supplies an abundance of information on acid-base physiology, disorders of acid-base equilibrium, and the management and treatment of these disorders in clinical practice. A unique and timely source, this guide provides a large number of tables, references, and figures to illustrate the relationship between the underlying physiology and diagnosis of acid-base disorders.