• With an abundance of reader-friendly diagrams and figures, this guide
• clearly describes the transmembrane flux of Na+, K+, Ca2+, and Cl- ions via channel proteins
• emphasizes the importance of ion channels in pulmonary vascular physiology and pathophysiology
• presents information on abnormal channel expression and function in the development of inheritable or acquired pulmonary vascular disease
• contains combined molecular biological, biophysical, and functional characterizations of ion channels

This volume presents a global overview of the role of ion flux via transmembrane ion channel proteins in the regulation of pulmonary vascular tone and in the vascular remodeling processes associated with pulmonary vascular disease-offering a comprehensive review of the multiple families of ion channels that have been identified and characterized in pulmonary artery smooth muscle, as well as a practical discussion of experimental tools for the study of ion channel physiology and molecular biology.