• Illustrates how a design idea for tissue engineering is developed through scientific methodology
• Focuses on basic bone biology
• Integrates fundamental sciences with tissue engineering
• Provides an assessment paradigm for tissue engineered therapies
• Includes in vitro animal model assessments, statistics, and biomechanics

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who address key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients.

In the first section, the contributors discuss the development of the skeletal system, cell lineage and progression, extracellular molecules, and the physiology of bone dynamics. The next section emphasizes the basic elements of bone, including signaling molecules and pathways and their regulatory interactions, an in-depth explanation of substrata, and scaffold design and development. Additional chapters focus on fundamental statistics, animal models and key outcome techniques in biomechanics and tissue morphology quantitation. The final three chapters address opportunities for tissue engineering and bone, as well as thematic opportunities for tissue engineering in the spine, craniofacial, and dental areas.

The comprehensive nature of this book, including extensive bibliographies, will make it an invaluable resource for biomedical engineers, tissue engineers, dental and bone-related medical researchers, and craniofacial biologists.